4/12/2023 0 Comments Insomnia help to sleepSerotonin receptor antagonists – activation of these receptors can interfere with deep sleep.Orexin receptor antagonists like suvorexant (Belsomra) that block wakefulness-promoting neuropeptides from binding their receptors.Drugs that target melatonin receptors (MT1 and MT2) such as ramelteon (Rozerem).What are Novel and Emerging Therapies for Insomnia? Antidepressants with sedative properties such as doxepin (Silenor), trazodone (Desyrel), and amitriptyline (Elavil).Benzodiazepine-like drugs such as zaleplon (Sonata), zolpidem (Ambien), and eszopiclone (Lunesta).Benzodiazepines such as alprazolam (Xanax), clonazepam (Klonipin), and diazepam (Valium).Over-the-counter drugs such as antihistamines for occasional use.What are Conventional Medical Treatments for Insomnia? Sleep restriction therapy, which limits the amount of time spent in bed.Avoid bedtime activities not related to sleep.What Lifestyle and Non-Pharmacological Changes Can Be Beneficial for Insomnia? Stimulants such as caffeine and nicotine.Certain medications such as decongestants, chemotherapy drugs, and beta-agonists.Physical health conditions such as cardiovascular disease and urinary and respiratory problems.Mental health problems such as anxiety, depression, and bipolar disorder.Female gender-hormonal shifts from menstruation, pregnancy, and menopause can contribute to sleeping problems.What are Causes and Risk Factors for Insomnia? Several natural interventions such as melatonin and valerian may help improve sleep and restore the body’s natural circadian rhythm. Insomnia may arise without any clear underlying cause (primary) or may be due to a comorbid condition (secondary), such as chronic pain that makes it difficult to sleep. Chronic insomnia, which lasts at least three days per week for three months or more, can have profound long-term effects on health. Sleep deficiency can not only significantly diminish quality of life, but may also increase risk of multiple health problems such as anxiety, cardiovascular disease, and obesity.Īcute or transient insomnia can last several days or weeks, often in response to a stressful life event. Insomnia can involve the inability to fall asleep (onset insomnia) or stay asleep (maintenance insomnia). Insomnia is a fairly common sleep disorder, affecting approximately 10% of Americans.
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